International Symposium Innate Immune Memory
May 29th-31st 2023, Naples, Italy 

Congress Venue at Parthenope Conference Centre
Università di Napoli Federico II, via Pathenope n. 36, Napoli, Italy 

Button 14 512Download here the final programme.

  Monday 29th of May
 10.00h Welcome – University Authorities & The Organizers: Giuseppe Matarese, Mihai Netea, Triantafyllos Chavakis, Siroon Bekkering, George Hajishengallis, Zoltan Fehervari
Mechanisms in regulating trained immunity 
Chairs: Jorge Dominguez Andres (Nijmegen-Netherlands) & Shih-chin Cheng (Xiamen-China)
10.15h Luis Barreiro  Systems immunology of innate immune responses 
10.45h Boris Novakovic – Mechanisms of trained immunity in endothelial cells
11.15h Triantafyllos Chavakis – Mechanisms of trained immunity in neutrophils
11.45h Judith Austermann – Core histone degradation drives immune tolerance in human monocytes (from submitted abstracts)
12.00h Lunch and Poster Session
Chairs: Jessica dos Santos (Nijmegen-Netherlands) & Claudio Procaccini (Napoli-Italy)
14.00h Keynote: Galit Alter – Systems serology and trained immunity
14.30h Aki Minoda – MUKIN (Germ-free) Mouse Ageing Atlas: Determining microbiota-dependent ageing signatures
15.00h Sarah J. Sun – BCG Vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow (from submitted abstracts)
15.15h Rachel Low – A paradoxical role of the MEK1/2-ERK-RSK signalling axis in the priming of macrophages (from submitted abstracts)
15.30h Coffee Break
16.00h Timothy Osborne – Intersection of trained immunity and metabolism in macrophages through SETDB2 (from submitted abstracts)
16.15h Huan Jin – NAMPT/NAD+ metabolic axis in macrophage promotes trained immunity-mediated antitumor activity (from submitted abstracts)
16.30h Keynote: Bali Pulendran – Systems innate vaccinology
17.00h-17.15h Cytosens Sponsored Talk -  Simona Maida – 7 Laser & 186 Detectors: ID7000 Spectral Cell Analyzer, Best in-Class High-Parameter Flow Cytometry
19.00h Get Together Welcome Reception


Tuesday 30th of May
  Molecular and cellular mechanisms in health and diseases
Chairs: Yenan Bryceson (Huddinge-Sweden) & Rob Arts (Nijmegen-Netherlands)
09.00h Michael Sieweke – Central trained immunity in progenitor cells
09.30h Musa Mhlanga – Epigenetics of trained immunity in myeloid cells
10.00h George Hajishengallis – The role of trained immunity in chronic diseases
10.30h Silvia Pires – TL1A promotes ILC3-dependent neutrophil activation and colitis associated cancer (from submitted abstracts)
10.45h Anne-Sophie Beignon – Orchestration of myelopoiesis, early innate myeloid responses, and long-term innate immune imprinting after vaccination (from submitted abstracts)
11.00h Coffee Break
11.30h Chiara Romagnani  Epigenetics of NK cell memory
12.00h Antoine Roquilly  Post-sepsis immunological effects on cancer
12.30h James Shih-chin Cheng – Malaria pigment hemozoin induces persistent myelopoiesis-bias and boosts host immunity (from submitted abstracts)
12.45h Viviane Bechtold – AS01B-adjuvanted vaccine promotes functional and epigenetic modifications in monocytes (from submitted abstracts)
13.00h Lunch and Poster Session
Trained immunity in vertebrates
Chairs: Anaisa Valido Ferreira (Nijmegen-Netherlands) & Sarah Sun (Chicago-USA)
14.30h Katherine King  Central trained immunity in mycobacterial infection
15.00h Steven Josefowicz  Epigenetic memory in innate immune cells post-COVID-19
15.30h Zhou Xing  Innate immune memory of resident macrophages
16.00h Coffee Break
16.30h Margarida C. Gomes – Training innate immunity in zebrafish using Shigella (from submitted abstracts)
16.45h Dane Parker – Staphylococcus aureus induces broadly protective innate memory in airway epithelial cells (from submitted abstracts
Editors corner

Zoltan Fehervari (Nature) & Jamie Wilson (Nature Immunology) - 
Navigating the difficult sea of top journal publications

18.00h Open discussion and Poster Session


Wednesday 31st of May
Trained immunity and disease
Chairs: Vinod Kumar (Nijmegen-Netherlands) & Eva Kaufmann (Kingston-Canada)
09.00h Peter Kurre  Leukemia and trained immunity
09.30h Siroon Bekkering – Trained immunity in cardiometabolic diseases
10.00h Liwu Li – Programming of innate immune memory: from exhaustion to rejuvenation
10.30h Coffee Break
11.00h Barbara Mariotti – Identification of a trained phenotype in circulating neutrophils from COPD patients (from submitted abstracts)
11.15h Jéssica C. dos Santos – HIV-1 elite controllers and their 1st degree family members show enhanced monocyte responsiveness through trained immunity (from submitted abstracts)
11.30h Sinu P. John – Innate Immune Training Enhances the Reactivation of Latently Infected HIV-1 from Monocytic Cell Lines (from submitted abstracts)
Trained immunity and treatment
Chairs: Athanasios Ziogas (Nijmegen-Netherlands) & Giuseppe Matarese (Napoli-Italy)
11.45h Giuseppe Matarese – Caloric restriction effects on innate immunity
12.15h Maziar Divangahi – Trained immunity on protection against tuberculosis
12.45h Keynote: Vishwa Deep Dixit  Immunity and aging
13.15h Words of goodbye